4-(4-Nitrophenyl)piperazin-1-ylethylamine → HCID 16038854, compound

HRID 1984174Notes

Reaction equation

HRID 1984174 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][CH2:17][NH2:18])[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([C:26]2[N:30]([C:31]([CH3:34])([CH3:33])[CH3:32])[N:29]=[C:28]([CH:35]=O)[CH:27]=2)=[CH:22][CH:21]=1>>[C:31]([N:30]1[C:26]([C:23]2[CH:22]=[CH:21][C:20]([Cl:19])=[CH:25][CH:24]=2)=[CH:27][C:28]([CH2:35][NH:18][CH2:17][CH2:16][N:13]2[CH2:12][CH2:11][N:10]([C:7]3[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=3)[CH2:15][CH2:14]2)=[N:29]1)([CH3:34])([CH3:33])[CH3:32]

Participants

3

Reactant 2

HCID 289138874-(4-Nitrophenyl)piperazin-1-ylethylamineHCID 866110605-(4-Chlorophenyl)-1-t-butylpyrazole-3-carbaldehyde

Product 1

HCID 16038854HCID 16038854, compoundYield 50.4%

Procedure

Compound 57 was prepared using the same method as that of Example 1 except that 4-(4-nitrophenyl)piperazin-1-ylethylamine and 5-(4-chlorophenyl)-1-t-butylpyrazole-3-carbaldehyde were used.

Sources & evidence

ORD record
ord-b42a81272ce34c48bf475021570c2be9
Source dataset
uspto-grants-2009_06
Patent number
US07544686B2

Reaction notes

Loading…