2-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamine → HCID 16038931, compound

HRID 1984178Notes

Reaction equation

HRID 1984178 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][NH2:16])[CH2:10][CH2:9]1.[C:17]([N:21]1[C:25]([CH2:26][CH:27]([CH3:29])[CH3:28])=[CH:24][C:23]([CH:30]=O)=[N:22]1)([CH3:20])([CH3:19])[CH3:18]>>[C:17]([N:21]1[C:25]([CH2:26][CH:27]([CH3:28])[CH3:29])=[CH:24][C:23]([CH2:30][NH:16][CH2:15][CH2:14][N:11]2[CH2:10][CH2:9][N:8]([C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[F:1])[CH2:13][CH2:12]2)=[N:22]1)([CH3:20])([CH3:19])[CH3:18]

Participants

3

Reactant 2

HCID 110095812-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamineHCID 224935831-Tert-butyl-5-iso-butyl-3-formylpyrazole

Product 1

HCID 16038931HCID 16038931, compoundYield 76.7%

Procedure

Compound 64 was prepared using the same method as that of Example 1 except that 4-(2-fluorophenyl)piperazin-1-ylethylamine and 1-t-butyl-5-iso-butylpyrazole-3-carbaldehyde were used.

Sources & evidence

ORD record
ord-839d0289bb8a476583b4fbeaa786dae1
Source dataset
uspto-grants-2009_06
Patent number
US07544686B2

Reaction notes

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