HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamine → 1-t-Butyl-3-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}aminomethyl-5-(4-methylphenyl)pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[4-(2-Fluorophenyl)piperazin-1-yl]ethanamine | HCID 11009581 | — |
| Reactant | 1-t-Butyl-5-(4-methylphenyl)pyrazole-3-carbaldehyde | HCID 86611059 | — |
| Product | 1-t-Butyl-3-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}aminomethyl-5-(4-methylphenyl)pyrazole | HCID 68973582 | 89.4% |
Reaction Steps
Compound 69 was prepared using the same method as that of Example 1 except that 4-(2-fluorophenyl)piperazin-1-ylethylamine and 1-t-butyl-5-(4-methylphenyl)pyrazole-3-carbaldehyde were used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544686B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-a5c50c8d55e842059b7ab47e01549f4f |
| Source note | uspto-grants-2009_06 |