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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984188Generated: November 4, 2026

2-(4-(3-Chlorophenyl)piperazin-1-yl)ethan-1-amine → 1-t-Butyl-3-{2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl}aminomethyl-5-propyl pyrazole

https://huagongshe.com/reaction/1984188

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-(3-Chlorophenyl)piperazin-1-yl)ethan-1-amineHCID 12726736—
Reactant5-Propyl-1-t-butylpyrazole-3-carbaldehydeHCID 86261095—
Product1-t-Butyl-3-{2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl}aminomethyl-5-propyl pyrazoleHCID 1603899876.5%

Reaction Steps

Compound 75 was prepared using the same method as that of Example 1 except that 4-(3-chlorophenyl)piperazin-1-ylethylamine and 5-propyl-1-t-butylpyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-0ddb83b803974e9489b3944b6fbc8547
Source noteuspto-grants-2009_06