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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984190Generated: October 25, 2026

2-(4-(3-Chlorophenyl)piperazin-1-yl)ethan-1-amine → 2-t-Butyl-5-iso-butyl-3-{2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl}aminomethylpyrazole

https://huagongshe.com/reaction/1984190

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-(3-Chlorophenyl)piperazin-1-yl)ethan-1-amineHCID 12726736—
Reactant2-t-Butyl-5-iso-butylpyrazole-3-carbaldehydeHCID 86611058—
Product2-t-Butyl-5-iso-butyl-3-{2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl}aminomethylpyrazoleHCID 1603907954.8%

Reaction Steps

Compound 78 was prepared using the same method as that of Example 1 except that 4-(3-chlorophenyl)piperazin-1-ylethylamine and 2-t-butyl-5-iso-butylpyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-3f8e320475814d6a8fb3e802bb82195f
Source noteuspto-grants-2009_06