2-(4-(3-Chlorophenyl)piperazin-1-yl)ethan-1-amine → HCID 16039080, compound

HRID 1984191Notes

Reaction equation

HRID 1984191 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][NH2:16])[CH2:10][CH2:9]2)[CH:5]=[CH:6][CH:7]=1.[CH2:17]([C:21]1[N:25]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[N:24]=[C:23]([CH:32]=O)[CH:22]=1)[CH:18]([CH3:20])[CH3:19]>>[CH2:17]([C:21]1[N:25]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[N:24]=[C:23]([CH2:32][NH:16][CH2:15][CH2:14][N:11]2[CH2:10][CH2:9][N:8]([C:4]3[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=3)[CH2:13][CH2:12]2)[CH:22]=1)[CH:18]([CH3:20])[CH3:19]

Participants

3

Reactant 2

HCID 127267362-(4-(3-Chlorophenyl)piperazin-1-yl)ethan-1-amineHCID 592816115-Isobutyl-1-phenyl-1H-pyrazole-3-carbaldehyde

Product 1

HCID 16039080HCID 16039080, compoundYield 47.7%

Procedure

Compound 79 was prepared using the same method as that of Example 1 except that 4-(3-chlorophenyl)piperazin-1-ylethylamine and 5-iso-butyl-1-phenylpyrazole-3-carbaldehyde were used.

Sources & evidence

ORD record
ord-aeddf74ec8e94fabbc32e799466f9d9b
Source dataset
uspto-grants-2009_06
Patent number
US07544686B2

Reaction notes

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