5-Methyl-1-phenylpyrazole-3-carbaldehyde → 3-{2-[4-(4-Chlorobenzhydryl)piperazin-1-yl]ethyl}aminomethyl-5-methyl-1-phenylpyrazole

HRID 1984193노트

반응식

HRID 1984193 반응식
[Cl:1][C:2]1[CH:23]=[CH:22][C:5]([CH:6]([N:13]2[CH2:18][CH2:17][N:16]([CH2:19][CH2:20][NH2:21])[CH2:15][CH2:14]2)[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.[CH3:24][C:25]1[N:29]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[N:28]=[C:27]([CH:36]=O)[CH:26]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:6]([N:13]2[CH2:14][CH2:15][N:16]([CH2:19][CH2:20][NH:21][CH2:36][C:27]3[CH:26]=[C:25]([CH3:24])[N:29]([C:30]4[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=4)[N:28]=3)[CH2:17][CH2:18]2)[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[CH:22][CH:23]=1

참가 물질

3

반응물 2

HCID 141352365-Methyl-1-phenylpyrazole-3-carbaldehydeHCID 142106204-(4-Chlorobenzhydryl)piperazin-1-ylethylamine

생성물 1

HCID 689734283-{2-[4-(4-Chlorobenzhydryl)piperazin-1-yl]ethyl}aminomethyl-5-methyl-1-phenylpyrazole수율 58%

실험 절차

Compound 92 was prepared using the same method as that of Example 1 except that 4-(4-chlorobenzhydryl)piperazin-1-ylethylamine and 5-methyl-1-phenylpyrazole-3-carbaldehyde were used.

출처 및 근거

ORD 기록
ord-94024ac8d6214cdcaf58cacb4b8c6584
출처 데이터셋
uspto-grants-2009_06
특허 번호
US07544686B2

반응 노트

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