HRID1984196

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14210620

未命名化合物

HCID22493583

未命名化合物

PRODUCTS

生成物

结构：CC(C)Cc1cc(CNCCN2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)nn1C(C)(C)C

HCID68972993

未命名化合物

收率 68%

PROCEDURE

实验过程

Compound 95 was prepared using the same method as that of Example 1 except that 4-(4-chlorobenzhydryl)piperazin-1-ylethylamine and 1-t-butyl-5-iso-butylpyrazole-3-carbaldehyde were used.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6a940035029b46908b5ef5d463f2b2e2
来源数据集: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07544686B2
来源说明: uspto-grants-2009_06

反应 SMILES

[Cl:1][C:2]1[CH:23]=[CH:22][C:5]([CH:6]([N:13]2[CH2:18][CH2:17][N:16]([CH2:19][CH2:20][NH2:21])[CH2:15][CH2:14]2)[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.[C:24]([N:28]1[C:32]([CH2:33][CH:34]([CH3:36])[CH3:35])=[CH:31][C:30]([CH:37]=O)=[N:29]1)([CH3:27])([CH3:26])[CH3:25]>>[C:24]([N:28]1[C:32]([CH2:33][CH:34]([CH3:35])[CH3:36])=[CH:31][C:30]([CH2:37][NH:21][CH2:20][CH2:19][N:16]2[CH2:15][CH2:14][N:13]([CH:6]([C:7]3[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:5]3[CH:4]=[CH:3][C:2]([Cl:1])=[CH:23][CH:22]=3)[CH2:18][CH2:17]2)=[N:29]1)([CH3:27])([CH3:26])[CH3:25]