4-(4-Chlorobenzhydryl)piperazin-1-ylethylamine → 3-{2-[4-(4-Chlorobenzhydryl)piperazin-1-yl]ethyl}aminomethyl-1,5-diphenylpyrazole

HRID 1984199Notes

Reaction equation

HRID 1984199 reaction equation
[Cl:1][C:2]1[CH:23]=[CH:22][C:5]([CH:6]([N:13]2[CH2:18][CH2:17][N:16]([CH2:19][CH2:20][NH2:21])[CH2:15][CH2:14]2)[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.[C:24]1([N:30]2[C:34]([C:35]3[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=3)=[CH:33][C:32]([CH:41]=O)=[N:31]2)[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:6]([N:13]2[CH2:14][CH2:15][N:16]([CH2:19][CH2:20][NH:21][CH2:41][C:32]3[CH:33]=[C:34]([C:35]4[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=4)[N:30]([C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)[N:31]=3)[CH2:17][CH2:18]2)[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 142106204-(4-Chlorobenzhydryl)piperazin-1-ylethylamineHCID 534070841,5-Diphenyl-1H-pyrazole-3-carbaldehyde

Product 1

HCID 689758873-{2-[4-(4-Chlorobenzhydryl)piperazin-1-yl]ethyl}aminomethyl-1,5-diphenylpyrazoleYield 61%

Procedure

Compound 98 was prepared using the same method as that of Example 1 except that 4-(4-chlorobenzhydryl)piperazin-1-ylethylamine and 1,5-diphenylpyrazole-3-carbaldehyde were used.

Sources & evidence

ORD record
ord-a97d3ed9f4e54536bb00f4d746d76c23
Source dataset
uspto-grants-2009_06
Patent number
US07544686B2

Reaction notes

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