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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1984204생성일: 2026년 10월 25일

Ethyl formate → Rac-5-isopropyl-2-oxo-cyclohexanecarbaldehyde

https://huagongshe.com/reaction/1984204

반응식

참여 물질

역할이름HCID투입량
반응물Ethyl formateHCID 8025—
반응물4-IsopropylcyclohexanoneHCID 79488—
반응물Sodium MethoxideHCID 10942334—
용매Diethyl EtherHCID 3283—
생성물Rac-5-isopropyl-2-oxo-cyclohexanecarbaldehydeHCID 54180615—

반응 단계

A solution of ethyl formate (6 mmol) in diethyl ether (2 ml) was added dropwise to a suspension of sodium methoxide (6 mmol) and 4-isopropyl-cyclohexanone (3 mmol) in absolute diethyl ether (3 ml) and after complete evolution of the gas the reaction mixture was stirred overnight at room temperature. The solid formed was filtered off, washed with diethyl ether and dried in a high vacuum. The product was obtained as a slightly yellow solid. tR 2.26; MS (pos. Ion.) m/z 169.32 [M+H]+. (J. Org. Chem. 2000, 65(21), 7145-7150).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07544691B2
출처 데이터셋uspto-grants-2009_06
ORD IDord-099bedd1ca284d7eb6695a69f9a6e3f8
출처 메모uspto-grants-2009_06