Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl formate → Rac-5-isopropyl-2-oxo-cyclohexanecarbaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl formate | HCID 8025 | — |
| 반응물 | 4-Isopropylcyclohexanone | HCID 79488 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | Rac-5-isopropyl-2-oxo-cyclohexanecarbaldehyde | HCID 54180615 | — |
반응 단계
A solution of ethyl formate (6 mmol) in diethyl ether (2 ml) was added dropwise to a suspension of sodium methoxide (6 mmol) and 4-isopropyl-cyclohexanone (3 mmol) in absolute diethyl ether (3 ml) and after complete evolution of the gas the reaction mixture was stirred overnight at room temperature. The solid formed was filtered off, washed with diethyl ether and dried in a high vacuum. The product was obtained as a slightly yellow solid. tR 2.26; MS (pos. Ion.) m/z 169.32 [M+H]+. (J. Org. Chem. 2000, 65(21), 7145-7150).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07544691B2 |
| 출처 데이터셋 | uspto-grants-2009_06 |
| ORD ID | ord-099bedd1ca284d7eb6695a69f9a6e3f8 |
| 출처 메모 | uspto-grants-2009_06 |