HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Chloro-propoxy)-2-nitro-benzene → 2-(3-Chloropropoxy)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Chloro-propoxy)-2-nitro-benzene | HCID 11424463 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(3-Chloropropoxy)aniline | HCID 10012643 | — |
Reaction Steps
1-(3-Chloro-propoxy)-2-nitro-benzene (˜60 mmol) is dissolved in ethanol (200 ml) and platinum dioxide (0.5 g) is added. The stirred mixture is treated with hydrogen under normal pressure until the hydrogen uptake stopped. The catalyst is filtered off and the filtrate is evaporated. A pale yellow oil with Rf=0.3 (CH2Cl2) is obtained, which is used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544688B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-d7a180a5fe524a9d97ad3909c1cdd35c |
| Source note | uspto-grants-2009_06 |