HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,5-Dimethyl-1H-pyrazole-3-carboxamide → 1,5-dimethyl-1H-pyrazole-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,5-Dimethyl-1H-pyrazole-3-carboxamide | HCID 17984159 | — |
| Solvent | Phosphorus oxychloride | HCID 24813 | — |
| Product | 1,5-dimethyl-1H-pyrazole-3-carbonitrile | HCID 12211891 | 89.4% |
Reaction Steps
The method described in Part E of Examples 1 through 4 was used to treat 1,5-dimethyl-1H-pyrazole-3-carboxamide (5.0 g, 36 mmol) with phosphorous oxychloride (20 mL) to afford 3.9 g of 1,5-dimethyl-1H-pyrazole-3-carbonitrile. A small portion was recrystallized from hexane to provide the following data.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544697B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-cc9e00bed9c840ef9d4a4dfb3bb41681 |
| Source note | uspto-grants-2009_06 |