HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → 5-ethyl-1-methyl-1H-pyrazole-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | Ethyl 5-ethyl-1-methyl-1H-pyrazole-3-carboxylate | HCID 22145397 | — |
| Product | 5-ethyl-1-methyl-1H-pyrazole-3-carboxamide | HCID 66958582 | — |
Reaction Steps
A mixture of ethyl 5-ethyl-1-methyl-1H-pyrazole-3-carboxylate (5.03 g, 27.6 mmol) and ammonium hydroxide (28 mL of 30%) was stirred for 18 hours at ambient temperature. A precipitate formed, was isolated by filtration, and washed with cold hexanes to provide 2.60 g of 5-ethyl-1-methyl-1H-pyrazole-3-carboxamide as a white solid, mp 170-172° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544697B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-46e51a4bd52d47d1bc1fcad4027ee9c9 |
| Source note | uspto-grants-2009_06 |