HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyridinamine, 5-bromo-6-methyl- → HCID 57718247, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyridinamine, 5-bromo-6-methyl- | HCID 170678 | — |
| Reactant | Benzenesulfonyl chloride, 2,4-dichloro- | HCID 204419 | — |
| Reactant | 4-(N-piperidinylsulfonyl)thiophenol | HCID 57718290 | — |
| Product | HCID 57718247 | HCID 57718247 | — |
Reaction Steps
Prepared from 2-amino-5-bromo-6-methylpyridine and 4-(N-piperidinylsulfonyl)thiophenol according to General Method 11 step 1 followed by reaction with 2,4-dichlorophenylsulfonyl chloride according to General Method 11 step 2. 1H NMR (CDCl3): 8.24, 7.76, 7.72, 7.51, 7.19, 7.05 (1H, 1H, 2H, 1H, 1H, 2H, 1H, 7×d, J 9, 11, 9, 11, 10, 9 Hz, Ar CH's), 7.63 (1H, s, A-ring CH ortho to 2×Cl), 3.10-3.01 (4H, m, CH2NCH2), 2.58 (3H, s, CH3), 1.76-1.68 (4H, m, CH2CH2CH2CH2CH2), 1.58-1.47 (2H, m, CH2CH2CH2CH2CH2). Hplc (Luna 2, Gradient 5): rt=6.40 minutes. LC/MS rt=7.11 minutes, 572/574 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544702B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-a46bafb5b6984343aadb643020115e9d |
| Source note | uspto-grants-2009_06 |