HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyridinamine, 5-bromo-6-methyl- → HCID 57718204, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyridinamine, 5-bromo-6-methyl- | HCID 170678 | — |
| Reactant | 2-Chloro-4-(trifluoromethyl)benzenesulfonyl chloride | HCID 2736675 | — |
| Reactant | 4-(N-piperidinylsulfonyl)thiophenol | HCID 57718290 | — |
| Product | HCID 57718204 | HCID 57718204 | — |
Reaction Steps
Prepared from 2-amino-5-bromo-6-methylpyridine and 4-(N-piperidinylsulfonyl)thiophenol according to General Method 11 step 1 followed by reaction with 2-chloro-4-trifluoromethylphenylsulfonyl chloride according to General Method 11 step 2. 1H NMR (CDCl3): 8.21 (1H, d, J 10 Hz, Ar CH ortho to SO2NH), 7.61-7.45 (5H, m, Ar CH's), 6.96 (2H, d, J 9 Hz, Ar CH's), 6.76 (1H, d, J 11 Hz, Ar CH), 2.86-2.78 (4H, m, CH2NCH2), 2.34 (3H, s, CH3), 1.53-1.41 (4H, m, CH2CH2CH2CH2CH2), 1.33-1.20 (2H, m, CH2CH2CH2CH2CH2). Hplc (Luna 2, Gradient 5): rt=6.47 minutes. LC/MS rt=7.04 minutes, 606 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544702B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-b807c38dfc6c4e66b25338aa12734c19 |
| Source note | uspto-grants-2009_06 |