反应详情

In analogy to the procedure described for the synthesis of Example 1, the title compound was synthesized from (4,4-difluoro-piperidin-1-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-methanone (intermediate 1) and bromoacetonitrile. The title compound was obtained in 38% yield as light green foam. MS (m/e): 445.2 (MH+, 100%).

1. customIn analogy to the procedure described for the synthesis of Example 1