HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic acid, 2-iodo-, methyl ester → HCID 24783671, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic acid, 2-iodo-, methyl ester | HCID 69132 | — |
| Reactant | 4-Ethynyl-5-methyl-3-phenyl-isoxazole | HCID 53434647 | — |
| Product | HCID 24783671 | HCID 24783671 | 82% |
Reaction Steps
As described for example 11c, 4-ethynyl-5-methyl-3-phenyl-isoxazole (110 mg, 0.60 mmol) was converted (using methyl 2-iodobenzoate instead of 2-chloro-4-iodopyridine) to the title compound (SiO2, heptane:ethyl acetate=100:0 to 80:20, 166 mg, 82%) which was obtained as an off-white solid. MS: m/e=318.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544704B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-9fc7baad4de6499b91ac362c602a7fa7 |
| Source note | uspto-grants-2009_06 |