HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Iodoaniline → HCID 24783672, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Iodoaniline | HCID 11995 | — |
| Reactant | 4-Ethynyl-5-methyl-3-phenyl-isoxazole | HCID 53434647 | — |
| Product | HCID 24783672 | HCID 24783672 | 85% |
Reaction Steps
As described for example 11c, 4-ethynyl-5-methyl-3-phenyl-isoxazole (110 mg, 0.60 mmol) was converted (using 2-iodo-aniline instead of 2-chloro-4-iodopyridine) to the title compound (SiO2, heptane:ethyl acetate=100:0 to 50:50, 139 mg, 85%) which was obtained as a light brown oil. MS: m/e=375.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544704B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-2874fedd645d4586aa2327264a571910 |
| Source note | uspto-grants-2009_06 |