反应详情

As described for example 11c, 4-ethynyl-5-methyl-3-phenyl-isoxazole (58 mg, 0.32 mmol) was converted (using 2-iodo-isonicotinic acid methyl ester instead of 2-chloro-4-iodopyridine) to the title compound (SiO2, heptane:ethyl acetate=95:5 to 0:100, 70 mg, 70%) which was obtained as a light brown solid. MS: m/e=319.1 [M+H]+.