HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-iodopyrimidine → HCID 68854113, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-iodopyrimidine | HCID 7006651 | — |
| Reactant | 4-Ethynyl-5-methyl-3-phenyl-isoxazole | HCID 53434647 | — |
| Product | HCID 68854113 | HCID 68854113 | 56% |
Reaction Steps
As described for example 11c, 4-ethynyl-5-methyl-3-phenyl-isoxazole (55 mg, 0.30 mmol) was converted (using 5-bromo-2-iodo-pyrimidine instead of 2-chloro-4-iodopyridine) to the title compound (SiO2, heptane:ethyl acetate=95:5 to 0:100, 58 mg, 56%) which was obtained as a light yellow solid. MS: m/e=341.9 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544704B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-2b72ffd068094c978f3e2ff0237b172d |
| Source note | uspto-grants-2009_06 |