HCID 45141475, compound → HCID 24784180, compound

Participants

Reaction Steps

As described for example 11c, 4-ethynyl-5-methyl-3-phenyl-isoxazole (92 mg, 0.50 mmol) was converted [using 2-iodo-1-methyl-5-phenyl-1H-imidazole (prepared from 1-methyl-5-phenyl-1H-imidazole according to J. Org. Chem. (43) 4381, 1978) instead of 2-chloro-4-iodopyridine] to the title compound (SiO2, heptane:ethyl acetate=95:5 to 0:100, 88 mg, 52%) which was obtained as a light brown solid. MS: m/e=340.2 [M+H]+.

Provenance & Evidence