2-Bromo-4-ethylpyridine → 4-Ethyl-2-(5-methyl-3-phenyl-isoxazol-4-ylethynyl)-pyridine

Beteiligte Stoffe

Reaktionsschritte

As described for example 11c, 4-ethynyl-5-methyl-3-phenyl-isoxazole (92 mg, 0.50 mmol) was converted (using 2-bromo-4-ethylpyridine instead of 2-chloro-4-iodopyridine) to the title compound (SiO2, heptane:ethyl acetate=95:5 to 0:100, 74 mg, 51%) which was obtained as a yellow oil. MS: m/e=289.1 [M+H]+.

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