HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-isopropylthiazole → HCID 68854104, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-isopropylthiazole | HCID 2763182 | — |
| Reactant | 4-Ethynyl-5-methyl-3-phenyl-isoxazole | HCID 53434647 | — |
| Product | HCID 68854104 | HCID 68854104 | 15% |
Reaction Steps
As described for example 11c, 4-ethynyl-5-methyl-3-phenyl-isoxazole (92 mg, 0.50 mmol) was converted (using 4-bromo-2-isopropylthiazole instead of 2-chloro-4-iodopyridine) to the title compound (SiO2, heptane:ethyl acetate=95:5 to 0:100, 23 mg, 15%) which was obtained as a yellow oil. MS: m/e=309.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544704B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-eae507702ae24e6e900ab236926bb86f |
| Source note | uspto-grants-2009_06 |