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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984810Generated: November 2, 2026

Pyridine → HCID 68867993, compound

https://huagongshe.com/reaction/1984810

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantCyclopentylacetyl chlorideHCID 3485182—
ReactantHCID 68870114HCID 68870114—
SolventDichloromethaneHCID 6344—
ProductHCID 68867993HCID 68867993519.6%

Reaction Steps

(S)-(2-Amino-5-bromo-benzoylamino)-3-(2′-phenoxy-biphenyl-4-yl)-propionic acid methyl ester (0.2 g, 0.04 mmlo) in 5 ml of DCM was reacted with cyclopentyl acetyl chloride (82.6 mg, 0.06 mmol) and pyridine (60 mg, 0.08 mmol) as described in general procedure K. The resulting ester was hydrolyzed according to the general procedure C to afford the title compound (0.2 g) as a white solid. LCMS: 642 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544699B2
Source datasetuspto-grants-2009_06
ORD IDord-762ea31fcb6a46fbbc68fad2e3fd2edf
Source noteuspto-grants-2009_06