HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 68867993, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Cyclopentylacetyl chloride | HCID 3485182 | — |
| Reactant | HCID 68870114 | HCID 68870114 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68867993 | HCID 68867993 | 519.6% |
Reaction Steps
(S)-(2-Amino-5-bromo-benzoylamino)-3-(2′-phenoxy-biphenyl-4-yl)-propionic acid methyl ester (0.2 g, 0.04 mmlo) in 5 ml of DCM was reacted with cyclopentyl acetyl chloride (82.6 mg, 0.06 mmol) and pyridine (60 mg, 0.08 mmol) as described in general procedure K. The resulting ester was hydrolyzed according to the general procedure C to afford the title compound (0.2 g) as a white solid. LCMS: 642 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544699B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-762ea31fcb6a46fbbc68fad2e3fd2edf |
| Source note | uspto-grants-2009_06 |