HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → 2-Amino-5-methoxybenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 6-methoxy-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione | HCID 294479 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Amino-5-methoxybenzamide | HCID 20338217 | — |
Reaction Steps
To a solution of 6-methoxy-1H-benzo[d][1.3]oxazine-2,4-dione (7.0 g, 36.2 mmol) in THF (50 mL) was added NH4OH (20 mL) and the reaction was stirred at rt for 1 h. The solution was concentrated under reduced pressure and dried to give 5.0 g of 2-amino-5-methoxy-benzamide as a dark brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544699B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-1db4b594fe5d4bde897be884d14c7dbc |
| Source note | uspto-grants-2009_06 |