HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18457633, compound → HCID 57717761, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18457633 | HCID 18457633 | — |
| Reactant | HCID 68869313 | HCID 68869313 | — |
| Product | HCID 57717761 | HCID 57717761 | 94.9% |
Reaction Steps
50 mg (0.12 mmol) of 7-(4-tert-butyl-phenoxy)-1-cyclopentylmethyl-isoquinoline-3-carboxylic acid (Example 419) was reacted with (2R)-amino-3-thiophen-3-yl-propionic acid methyl ester HCl (28.1 mg, 0.14 mmol) as described in general procedure A. The resulting ester was hydrolyzed as described in general procedure C to afford 63.4 mg of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544699B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-c90866c1c581435c97577bf005eaf404 |
| Source note | uspto-grants-2009_06 |