HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18457633, compound → HCID 68870083, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18457633 | HCID 18457633 | — |
| Reactant | 79777-81-4 | HCID 86619129 | — |
| Product | HCID 68870083 | HCID 68870083 | 88.7% |
Reaction Steps
50 mg (0.12 mmol) of 7-(4-tert-butyl-phenoxy)-1-cyclopentylmethyl-isoquinoline-3-carboxylic acid (Example 419) was reacted with (2S)-amino-4, 4-dimethyl-pentanoic acid methyl ester HCL (26.4 mg, 0.14 mmol) as described in general procedure A. The resulting ester was hydrolyzed as described in general procedure C to afford 56.5 mg of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544699B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-0fbc7319ebf9480e986b74e77f34c141 |
| Source note | uspto-grants-2009_06 |