HCID 18457633, compound → HCID 57717684, compound

Participants

Reaction Steps

50 mg (0.12 mmol) of 7-(4-tert-butyl-phenoxy)-1-cyclopentylmethyl-isoquinoline-3-carboxylic acid (Example 419) was reacted with (2S)-amino-3-(4-tert-butyl-phenyl)-propionic acid methyl ester HCl (36.8 mg, 0.14 mmol) as described in general procedure A. The resulting ester was hydrolyzed as described in general procedure C to afford 71.4 mg of the title compound as a white solid.

Provenance & Evidence