HRID1984849

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8635

Methyl 2-aminobenzoate

C8H9NO2

反应SMILES：CC(C)(C)c1ccc(Oc2ccc3cc(C(=O)Cl)nc(CC4CCCC4)c3c2)cc1

HCID86597133

未命名化合物

PRODUCTS

产物

反应SMILES：CC(C)(C)c1ccc(Oc2ccc3cc(C(=O)Nc4ccccc4C(=O)O)nc(CC4CCCC4)c3c2)cc1

HCID57717920

未命名化合物

收率 57.4%

PROCEDURE

实验过程

The title compound (30 mg) was prepared following the same procedures that was described for example 432 from methyl-2-aminobenzoate (0.1 mmol, 15.1 mg) and 7-(4-tert-butyl-phenoxy)-1-cyclopentylmethyl-isoquinoline-3-carbonyl chloride (46 mg, 0.1 mmol).

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-7028071934724ff2a5033b5e87de2789
来源数据集: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07544699B2
来源说明: uspto-grants-2009_06

反应SMILES

C[O:2][C:3](=[O:11])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH2:10].[C:12]([C:16]1[CH:41]=[CH:40][C:19]([O:20][C:21]2[CH:30]=[C:29]3[C:24]([CH:25]=[C:26]([C:37](Cl)=[O:38])[N:27]=[C:28]3[CH2:31][CH:32]3[CH2:36][CH2:35][CH2:34][CH2:33]3)=[CH:23][CH:22]=2)=[CH:18][CH:17]=1)([CH3:15])([CH3:14])[CH3:13]>>[C:12]([C:16]1[CH:41]=[CH:40][C:19]([O:20][C:21]2[CH:30]=[C:29]3[C:24]([CH:25]=[C:26]([C:37]([NH:10][C:5]4[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=4[C:3]([OH:2])=[O:11])=[O:38])[N:27]=[C:28]3[CH2:31][CH:32]3[CH2:33][CH2:34][CH2:35][CH2:36]3)=[CH:23][CH:22]=2)=[CH:18][CH:17]=1)([CH3:15])([CH3:13])[CH3:14]