HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cyclopentylacetic acid → 2-(2-Cyclopentyl-acetylamino)-3-(3-hydroxy-phenyl)-propionic acid methyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cyclopentylacetic acid | HCID 71606 | — |
| Edukt | Methyl 2-amino-3-(3-hydroxyphenyl)propanoate | HCID 22386100 | — |
| Produkt | 2-(2-Cyclopentyl-acetylamino)-3-(3-hydroxy-phenyl)-propionic acid methyl ester | HCID 68871419 | 54,9% |
Reaktionsschritte
12.5 g (54.3 mmol) of 2-amino-3-(3-hydroxy-phenyl)-propionic acid methyl ester was reacted with cyclopentyl acetic acid (6.97 g, 54.3 mmol) as described in general procedure A. The compound was purified using gradient elution with 10% to 100% ethyl acetate in hexanes to yield 9.1 g of 2-(2-cyclopentyl-acetylamino)-3-(3-hydroxy-phenyl)-propionic acid methyl ester.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07544699B2 |
| Quelldatensatz | uspto-grants-2009_06 |
| ORD ID | ord-0e04959f4fa84717a0fc12d0baa3e2cf |
| Quellennotiz | uspto-grants-2009_06 |