HCID 57718920, compound → HCID 57719093, compound

Participants

Reaction Steps

A solution of 5-[3-(4-methoxy-phenyl)-propyl]-3-(4-methyl-benzyl)-1-propyl-imidazolidine-2,4-dione (1.26 g, 3.19 mmol) in THF (20 ml) was treated dropwise with 1 M solution of borane-THF complex in THF (16 mL, 16 mmol) and then stirred at room temperature under N2 for 22 h. The reaction was quenched with methanol (20 mL) and stirred at room temperature for 2 hr. The solvent was removed in vacuo to give 1.25 g (100%) crude 4-[3-(4-methoxy-phenyl)-propyl]-1-(4-methyl-benzyl)-3-propyl-imidazolidin-2-one that was carried on without purification. MS (ES+) Calc'd for C24H33N2O2 (M+1) 381. Found m/z 381 (100%). 1H NMR.

Provenance & Evidence