2-(Chloromethyl)quinoline → HCID 10217381, compound

HRID 1985277Notes

Reaction equation

HRID 1985277 reaction equation
C[O:2][C:3](=[O:25])[C:4]([CH3:24])([O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][CH2:15][CH:16]2[CH2:20][NH:19][C:18](=[O:21])[N:17]2[CH3:22])=[CH:9][C:8]=1[CH3:23])[CH3:5].Cl[CH2:27][C:28]1[CH:37]=[CH:36][C:35]2[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=2)[N:29]=1>>[CH3:24][C:4]([O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][CH2:15][CH:16]2[CH2:20][N:19]([CH2:27][C:28]3[CH:37]=[CH:36][C:35]4[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=4)[N:29]=3)[C:18](=[O:21])[N:17]2[CH3:22])=[CH:9][C:8]=1[CH3:23])([CH3:5])[C:3]([OH:25])=[O:2]

Participants

3

Reactant 2

HCID 203942-(Chloromethyl)quinolineHCID 68867342HCID 68867342, compound

Product 1

HCID 10217381HCID 10217381, compound

Procedure

The titled compound was prepared using 2-Methyl-2-{2-methyl-4-[3-(3-methyl-2-oxo-imidazolidin-4-yl)-propyl]-phenoxy}-propionic acid methyl Ester (0.100 g, 0.287 mmole) and 2-chloromethyl-quinoline (0.092 g, 0.431 mmole) to produce an oil (0.023 g, 17%). Mass [EI+] 476 (M+H)+, [EI−] 474 (M−H)−.

Sources & evidence

ORD record
ord-90c6d4749f404a16b2c4b55faea64905
Source dataset
uspto-grants-2009_06
Patent number
US07544812B2

Reaction notes

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