2,4-Difluorophenyl isocyanate → HCID 57719823, compound

HRID 1985326Notes

Reaction equation

HRID 1985326 reaction equation
[OH:1][CH2:2][CH2:3][C:4]1[CH:5]=[C:6]([CH2:12][CH:13]([O:19][CH:20]([CH3:22])[CH3:21])[C:14]([O:16]CC)=[O:15])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11].[F:23][C:24]1[CH:29]=[C:28]([F:30])[CH:27]=[CH:26][C:25]=1[N:31]=[C:32]=[O:33]>>[F:23][C:24]1[CH:29]=[C:28]([F:30])[CH:27]=[CH:26][C:25]=1[NH:31][C:32]([O:1][CH2:2][CH2:3][C:4]1[CH:5]=[C:6]([CH2:12][CH:13]([O:19][CH:20]([CH3:21])[CH3:22])[C:14]([OH:16])=[O:15])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11])=[O:33]

Participants

3

Reactant 2

HCID 5932582,4-Difluorophenyl isocyanateHCID 22927032HCID 22927032, compound

Product 1

HCID 57719823HCID 57719823, compound

Procedure

Using ethyl 3-[3-(2-hydroxyethyl)-4-methoxyphenyl]-2-isopropoxypropanoate and 2,4-difluorophenylisocyanate, the title compound was obtained in the same manner as described in Example 148.

Sources & evidence

ORD record
ord-21c64dc017bd4b0993cf04cb64ac27a2
Source dataset
uspto-grants-2009_06
Patent number
US07544835B2

Reaction notes

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