3-Methoxyphenyl isocyanate → Dimethyl 2-[3-({[(3-methoxyanilino)carbonyl]-oxy)methyl)benzyl]malonate

HRID 1985340Notes

Reaction equation

HRID 1985340 reaction equation
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:16]=[CH:17][CH:18]=1)[CH2:6][CH:7]([C:12]([O:14][CH3:15])=[O:13])[C:8]([O:10][CH3:11])=[O:9].[CH3:19][O:20][C:21]1[CH:22]=[C:23]([N:27]=[C:28]=[O:29])[CH:24]=[CH:25][CH:26]=1>>[CH3:19][O:20][C:21]1[CH:22]=[C:23]([CH:24]=[CH:25][CH:26]=1)[NH:27][C:28]([O:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:16]=[CH:17][CH:18]=1)[CH2:6][CH:7]([C:8]([O:10][CH3:11])=[O:9])[C:12]([O:14][CH3:15])=[O:13])=[O:29]

Participants

3

Reactant 2

HCID 878433-Methoxyphenyl isocyanateHCID 22926882Dimethyl 2-[3-(hydroxymethyl)benzyl]malonate

Product 1

HCID 57719648Dimethyl 2-[3-({[(3-methoxyanilino)carbonyl]-oxy)methyl)benzyl]malonate

Procedure

Using dimethyl 2-[3-(hydroxymethyl)benzyl]malonate and 3-methoxyphenylisocyanate, the title compound was obtained in the same manner as described in Example 192b).

Sources & evidence

ORD record
ord-8c4614faaf1f4521911939f0b6103dc8
Source dataset
uspto-grants-2009_06
Patent number
US07544835B2

Reaction notes

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