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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 198537Generated: October 28, 2026

Ethyl Acetate → 4'-{[5-[6-(cyclopropylmethoxy)pyridin-3-yl]-4-methyl-6-oxo-2-propylpyrimidin-1(6H)-yl]methyl}-3'-fluorobiphenyl-2-carbonitrile

https://huagongshe.com/reaction/198537

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
ReactantCarbonate IonHCID 19660—
Reactant1,4-DioxaneHCID 31275—
ReactantCesium cationHCID 104967—
Reactant(6-(Cyclopropylmethoxy)pyridin-3-yl)boronic acidHCID 53216591—
Reactant4'-[(5-bromo-4-methyl-6-oxo-2-propylpyrimidin-1(6H)-yl)methyl]-3'-fluorobiphenyl-2-carbonitrileHCID 57460968—
Product4'-{[5-[6-(cyclopropylmethoxy)pyridin-3-yl]-4-methyl-6-oxo-2-propylpyrimidin-1(6H)-yl]methyl}-3'-fluorobiphenyl-2-carbonitrileHCID 57461052—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-2192b61dd3d6408a8f3bf78b9c96a78e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)