2,4-Difluorophenyl isocyanate → HCID 57719489, compound

HRID 1985371Notes

Reaction equation

HRID 1985371 reaction equation
[OH:1][CH2:2][CH2:3][C:4]1[CH:5]=[C:6]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[CH2:7][CH:8]([C:13]([O:15][CH3:16])=[O:14])[C:9]([O:11][CH3:12])=[O:10].[F:22][C:23]1[CH:28]=[C:27]([F:29])[CH:26]=[CH:25][C:24]=1[N:30]=[C:31]=[O:32]>>[F:22][C:23]1[CH:28]=[C:27]([F:29])[CH:26]=[CH:25][C:24]=1[NH:30][C:31]([O:1][CH2:2][CH2:3][C:4]1[CH:5]=[C:6]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[CH2:7][CH:8]([C:9]([O:11][CH3:12])=[O:10])[C:13]([O:15][CH3:16])=[O:14])=[O:32]

Participants

3

Reactant 2

HCID 5932582,4-Difluorophenyl isocyanateHCID 22926832HCID 22926832, compound

Product 1

HCID 57719489HCID 57719489, compound

Procedure

Using dimethyl 2-[3-(2-hydroxyethyl)-4-methoxybenzyl]-malonate and 2,4-difluorophenylisocyanate, the title compound was obtained in the same manner as described in Example 192b)

Sources & evidence

ORD record
ord-5e168b45fb924372a8a1cce889af4365
Source dataset
uspto-grants-2009_06
Patent number
US07544835B2

Reaction notes

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