Phenyl isocyanate → Dimethyl 2-(3-{[(anilinocarbonyl)oxy]methyl}-4-ethoxybenzyl)malonate

HRID 1985373Notes

Reaction equation

HRID 1985373 reaction equation
[CH2:1]([O:3][C:4]1[CH:19]=[CH:18][C:7]([CH2:8][CH:9]([C:14]([O:16][CH3:17])=[O:15])[C:10]([O:12][CH3:13])=[O:11])=[CH:6][C:5]=1[CH2:20][OH:21])[CH3:2].[C:22]1([N:28]=[C:29]=[O:30])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[NH:28]([C:29]([O:21][CH2:20][C:5]1[CH:6]=[C:7]([CH:18]=[CH:19][C:4]=1[O:3][CH2:1][CH3:2])[CH2:8][CH:9]([C:14]([O:16][CH3:17])=[O:15])[C:10]([O:12][CH3:13])=[O:11])=[O:30])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 7672Phenyl isocyanateHCID 22926717Dimethyl 2-[4-ethoxy-3-(hydroxymethyl)benzyl]malonate

Product 1

HCID 57719425Dimethyl 2-(3-{[(anilinocarbonyl)oxy]methyl}-4-ethoxybenzyl)malonate

Procedure

Using dimethyl 2-[4-ethoxy-3-(hydroxymethyl)benzyl]-malonate and phenylisocyanate, the title compound was obtained in the same manner as described in Example 192b).

Sources & evidence

ORD record
ord-beb681e4f2f14a869014e8e2dc2b84d1
Source dataset
uspto-grants-2009_06
Patent number
US07544835B2

Reaction notes

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