Benzene, 1-chloro-3-isocyanato- → Dimethyl 2-[3-({[(3-chloroanilino)carbonyl]oxy}methyl)-4-ethoxybenzyl]malonate

HRID 1985381Notes

Reaction equation

HRID 1985381 reaction equation
[CH2:1]([O:3][C:4]1[CH:19]=[CH:18][C:7]([CH2:8][CH:9]([C:14]([O:16][CH3:17])=[O:15])[C:10]([O:12][CH3:13])=[O:11])=[CH:6][C:5]=1[CH2:20][OH:21])[CH3:2].[Cl:22][C:23]1[CH:24]=[C:25]([N:29]=[C:30]=[O:31])[CH:26]=[CH:27][CH:28]=1>>[Cl:22][C:23]1[CH:24]=[C:25]([CH:26]=[CH:27][CH:28]=1)[NH:29][C:30]([O:21][CH2:20][C:5]1[CH:6]=[C:7]([CH:18]=[CH:19][C:4]=1[O:3][CH2:1][CH3:2])[CH2:8][CH:9]([C:14]([O:16][CH3:17])=[O:15])[C:10]([O:12][CH3:13])=[O:11])=[O:31]

Participants

3

Reactant 2

HCID 17968Benzene, 1-chloro-3-isocyanato-HCID 22926717Dimethyl 2-[4-ethoxy-3-(hydroxymethyl)benzyl]malonate

Product 1

HCID 57719439Dimethyl 2-[3-({[(3-chloroanilino)carbonyl]oxy}methyl)-4-ethoxybenzyl]malonate

Procedure

Using dimethyl 2-[4-ethoxy-3-(hydroxymethyl)benzyl]-malonate and 3-chlorophenylisocyanate, the title compound was obtained in the same manner as described in Example 192b).

Sources & evidence

ORD record
ord-d3545a9a5f1f4073899c1644e9f312a2
Source dataset
uspto-grants-2009_06
Patent number
US07544835B2

Reaction notes

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