HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethoxybenzaldehyde → (4S)-3-[(3R,2S)-3-(4-ethoxyphenyl)-3-hydroxy-2-isopropoxypropanoyl]-4-benzyl-1,3-oxazolan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethoxybenzaldehyde | HCID 24834 | — |
| Reactant | (4S)-4-benzyl-3-(2-isopropoxyacetyl)oxazolidin-2-one | HCID 59997951 | — |
| Product | (4S)-3-[(3R,2S)-3-(4-ethoxyphenyl)-3-hydroxy-2-isopropoxypropanoyl]-4-benzyl-1,3-oxazolan-2-one | HCID 57719757 | 105.4% |
Reaction Steps
Under the similar conditions to those described in Production example 332a), 2.4 g of 4-ethoxybenzaldehyde and 5.6 g of (4S)-4-benzyl-3-(2-isopropoxyacetyl)-1,3-oxazolidin-2-one were reacted, to give 7.2 g of (4S)-3-[(3R,2S)-3-(4-ethoxyphenyl)-3-hydroxy-2-isopropoxypropanoyl]-4-benzyl-1,3-oxazolan-2-one as a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544835B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-c122805ea83c4a2c942bc278ceb737ab |
| Source note | uspto-grants-2009_06 |