HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(piperidin-4-yl)-3,4-dihydroquinolin-2(1H)-one → 3-(piperazin-1-yl)-3,4-dihydroquinolin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(piperidin-4-yl)-3,4-dihydroquinolin-2(1H)-one | HCID 18321246 | — |
| Reactant | tert-Butyl 4-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)piperazine-1-carboxylate | HCID 59732047 | — |
| Product | 3-(piperazin-1-yl)-3,4-dihydroquinolin-2(1H)-one | HCID 59731943 | — |
Reaction Steps
tert-Butyl 4-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)piperazine-1-carboxylate (640 mg, 1.9 mmol) was reacted in a manner analogous to the preparation of 3-(piperidin-4-yl)-3,4-dihydroquinolin-2(1H)-one. Title compound was obtained as light brown solid in quantitative yield. MS m/e (M+H)+=232.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544680B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-9068adb82d8442228c359a310d7bc68b |
| Source note | uspto-grants-2009_06 |