HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → (1R,8S)-5-(2,2-Dimethyl-propyl)-1,11,11-trimethyl-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2(7),3,5-triene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Camphoroquinone | HCID 641916 | — |
| Reactant | (4,4-Dimethyl-2-oxo-pentyl)-phosphonic acid dimethyl ester | HCID 25112585 | — |
| Product | (1R,8S)-5-(2,2-Dimethyl-propyl)-1,11,11-trimethyl-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2(7),3,5-triene | HCID 69059732 | — |
Reaction Steps
white solid. MS (ESI): 259.1 (MH+). Prepared from (1R,4S)-1,7,7-trimethyl-bicyclo[2.2.1]heptane-2,3-dione, (4,4-dimethyl-2-oxo-pentyl)-phosphonic acid dimethyl ester, hydrazine monohydrate. Minor product, regioisomer of compound of example 22, isolated and purified by silica gel chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07547697B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-0a66d3d56a3346c184ff2578d079245a |
| Source note | uspto-grants-2009_06 |