HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → (1R,8S)-5-tert-Butyl-1,11,11-trimethyl-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2(7),3,5-triene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Camphoroquinone | HCID 641916 | — |
| Reactant | Dimethyl (3,3-dimethyl-2-oxobutyl)phosphonate | HCID 14302170 | — |
| Product | (1R,8S)-5-tert-Butyl-1,11,11-trimethyl-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2(7),3,5-triene | HCID 69061134 | — |
Reaction Steps
light yellow oil. MS (ESI): 245.2 (MH+). Prepared from (1R,4S)-1,7,7-trimethyl-bicyclo[2.2.1]heptane-2,3-dione, (3,3-dimethyl-2-oxo-butyl)-phosphonic acid dimethyl ester, hydrazine monohydrate. Minor product, regioisomer of compound of example 24, isolated and purified by silica gel chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07547697B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-7c34052b10674fc3b0b968e3b43da471 |
| Source note | uspto-grants-2009_06 |