HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexene → 2-AMino-5-(4-Methyl-1-piperazinyl)benzoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexene | HCID 8079 | — |
| Reactant | HCID 28400013 | HCID 28400013 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-AMino-5-(4-Methyl-1-piperazinyl)benzoic Acid | HCID 50989007 | 43.8% |
Reaction Steps
The mixture of 9 g of 2-nitro-5-(4-methylpiperazino)benzoic acid, 20 mL of cyclohexene and 3.5 g of Pd/C (10%) is heated under reflux conditions in 120 mL of ethanol for 6 hours. The hot reaction mixture is filtered through celite filter. The filtrate is evaporated to obtain 3.5 g of the title compound. m.p.: 212° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07547696B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-41e77538269b4de59a413bd4bd36acd4 |
| Source note | uspto-grants-2009_06 |