HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Thienylmethyl)amine → 2-Amino-3-cyano-4-[2-thienylmethylamino]-6-dimethylaminoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Thienylmethyl)amine | HCID 34005 | — |
| Reactant | 2-Amino-3-cyano-4-chloro-6-dimethylaminoquinoline | HCID 66850378 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Amino-3-cyano-4-[2-thienylmethylamino]-6-dimethylaminoquinoline | HCID 66850567 | — |
Reaction Steps
3 g of 2-amino-3-cyano-4-chloro-6-dimethylaminoquinoline and 6 mL of 2-thienylmethylamine are stirred at 125° C. for 3 hours. The reaction mixture is poured onto 30 mL of water. The precipitated material is filtered off, washed with 20 mL of water. After drying 1.9 g of the title compound is obtained, m.p.: 211° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07547696B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-43cb0153b72c4bbf9b32879c3defd0ab |
| Source note | uspto-grants-2009_06 |