HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1985698Generated: October 28, 2026
Benzylamine → 2-Amino-3-cyano-4-benzylamino-6-nitroquinoline
https://huagongshe.com/reaction/1985698
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | 2-Amino-3-cyano-4-chloro-6-nitroquinoline | HCID 66850601 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Amino-3-cyano-4-benzylamino-6-nitroquinoline | HCID 66850481 | — |
Reaction Steps
A mixture of 7 g of 2-amino-3-cyano-4-chloro-6-nitroquinoline and 30 mL of benzylamine was stirred at 55° C. for 1.5 hours. The reaction mixture is poured onto 30 mL of water. The precipitated material is filtered off, washed with water to give 7 g of the title compound, m.p.: 280-283° C. LC-MS: MH+ 2320; Ret. time: 5.19 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07547696B2 |
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| Source dataset | uspto-grants-2009_06 |
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| ORD ID | ord-f9aab62b52e5416897e453cb450a1f30 |
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| Source note | uspto-grants-2009_06 |
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