Novoldiamine → HCID 86602735, compound
Reaction equation
[Cl:1][C:2]1[N:11]=[C:10](Cl)[C:9]2[C:4](=[CH:5][C:6]([Cl:13])=[CH:7][CH:8]=2)[N:3]=1.[CH2:14]([N:16]([CH2:23][CH3:24])[CH2:17][CH2:18][CH2:19][CH:20]([NH2:22])[CH3:21])[CH3:15]>>[Cl:1][C:2]1[N:11]=[C:10]([NH:22][CH:20]([CH3:21])[CH2:19][CH2:18][CH2:17][N:16]([CH2:23][CH3:24])[CH2:14][CH3:15])[C:9]2[C:4](=[CH:5][C:6]([Cl:13])=[CH:7][CH:8]=2)[N:3]=1Participants
3
Procedure
Analogously to example 17, 2,4,7-trichloro-quinazoline is reacted with N1,N1-diethyl-pentane-1,4-diamine to give N4-(2,7-dichloro-quinazolin-4-yl)-N1,N1-diethyl-pentane-1,4-diamine and is further reacted
Sources & evidence
- ORD record
- ord-877739448b664fbb891032eb7415c4b2
- Source dataset
- uspto-grants-2009_06
- Patent number
- US07547702B2
Reaction notes
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