HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 67237126, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1,3-Bis(diphenylphosphino)propane | HCID 81219 | — |
| Reactant | HCID 67238425 | HCID 67238425 | — |
| Reactant | HCID 178418416 | HCID 178418416 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Product | HCID 67237126 | HCID 67237126 | — |
Reaction Steps
The product of step 1 was carbonylated in methanol with carbon monoxide (35 bar) at 110° C. (24 h) in the presence of palladium acetate (0.02 eq), dppp (0.025 eq) and triethylamine (3 eq). The solvent was evaporated and the residue was purified by chromatography on silica gel with ethyl acetate:heptane to yield the title compound as with crystals (MS: 346.3 (M+H+))
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07547699B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-ae169ecc79224e81a52eb70432b74a07 |
| Source note | uspto-grants-2009_06 |