P-Anisidine → HCID 178492142, compound

Participants

Reaction Steps

2,3-dihydroxypyridine (0.0021 Mol), p-methoxyaniline (0.0027 mol), p-sulfoaminoaniline (0.0027 mol) and NaIO3 (0.0009 mol) were dissolved in 160 ml of water/acetone (80:1, v/v) solvent. The reaction mixture was stirred for 4 hours, and maintained still overnight. 5-p-methoxyphenylamino-6-(p-sulfoaminophenylamino)-2,3-pyridindione and 6-p-methoxyphenylamino-5-(p-sulfoaminophenylamino)-2,3-pyridindione were purified by passing the filtered reaction mixture through a silica gel column (100-200 mesh). The yield was 12%-16%. 5,6-di(p-methoxyphenylamino)-2,3-pyridindione and 5,6-di(p-sulfoaminophenylamino)-2,3-pyridindione can also be obtained.

Provenance & Evidence