HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67392363, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 8-(2,2,2-Trifluoroethyl)-1,4-dioxa-8-azaspiro[4.5]decane | HCID 67007162 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 67392363 | HCID 67392363 | — |
Reaction Steps
8-(2,2,2-Trifluoroethyl)-1,4-dioxa-8-aza-spiro[4.5]decane (3.7 g, 16 mmol) was added to a solution of 5% HCl (45 mL) and acetone (8 mL). After refluxing for 12 h, the solvent was removed to give crude 1-(2,2,2-trifluoroethyl)piperidin-4-one hydrochloride which was used in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07547701B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-9de26e86b19f4c29a729d3a885345143 |
| Source note | uspto-grants-2009_06 |