3,5-Dimethyl-4-hydroxybenzaldehyde → 1-(4-Methoxy-3-fluorophenyl)-3-(4-hydroxy-3,5-dimethylphenyl)prop-2-en-1-one

HRID 1985921Notes

Reaction equation

HRID 1985921 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9](=[O:11])[CH3:10])=[CH:5][C:4]=1[F:12].[CH3:13][C:14]1[CH:15]=[C:16]([CH:19]=[C:20]([CH3:23])[C:21]=1[OH:22])[CH:17]=O>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9](=[O:11])[CH:10]=[CH:17][C:16]2[CH:19]=[C:20]([CH3:23])[C:21]([OH:22])=[C:14]([CH3:13])[CH:15]=2)=[CH:5][C:4]=1[F:12]

Participants

3

Reactant 2

HCID 752223,5-Dimethyl-4-hydroxybenzaldehydeHCID 968281-(3-Fluoro-4-methoxyphenyl)ethan-1-one

Product 1

HCID 690538851-(4-Methoxy-3-fluorophenyl)-3-(4-hydroxy-3,5-dimethylphenyl)prop-2-en-1-one

Procedure

This compound was synthesized from 4′-methoxy-3′-fluoroacetophenone and 3,5-dimethyl-4-hydroxybenzaldehyde according to general method 1 described earlier.

Sources & evidence

ORD record
ord-bca2f4260da94e43b095d52a31f97426
Source dataset
uspto-grants-2009_06
Patent number
US07547729B2

Reaction notes

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